Protein Glycosylation Workshop

Challenges and Opportunities for Optimising Protein Glycosylation
Tuesday February 9th 2016, Imperial College London

Increasing efforts are underway to produce recombinant proteins that have a homogeneous glycan profile, which will lead to products with improved in vivo characteristics (such as half‐life and efficacy) and hence offer substantial cost benefits. Studies involve the genetic engineering of cell lines, process modifications (for example, the addition of relevant precursors) and in vitro modification of recombinant proteins. These efforts will also facilitate the use of quality by design framework for the development of biologics.

This event, jointly supported by IBCarb and BioProNET (two BBRSC networks in Biotechnology and Bioenergy), aims to bring together researchers involved in recombinant protein production with scientists involved in product characterisation.

The workshop will feature keynote speakers as well as round table discussions to identify the grand challenges that arise from the production, regulation and technical aspects of recombinant protein glycosylation.  Attendees should also have the opportunity to form working groups for funding applications.

Confirmed speakers include David James (University of Sheffield) and Mitul Patel (GlaxoSmithKline).

Travel bursaries:
A number of travel bursaries are available for early-stage career researchers (PhD students and post-docs) to attend this event. For more information about travel bursaries from IBCarb please see www.ibcarb.com/funding or contact Claire Doherty. For travel bursaries from BioProNET please contact Charlotte Harrison.

For more information and to register for the event please use this link. Please register no later than Monday February 1st.

A growing membership

We currently have around 530 members, of which over 35% come from industry and non-university institutions. Around 80 different companies — from SMEs to large multinationals — have employees who are members of BioProNET. The word cloud below represents companies from which we have members. If you’d like to join them, click here.
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Our members come from almost all corners of the UK – see the member map below. In addition, we have members in Ireland, China, Kenya, USA, France and Malaysia.

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2nd Annual Scientific Meeting

October 22nd–23rd 2015, Manchester Midland Hotel

Our second annual scientific meeting was held at the Midland Hotel, Manchester on October 22nd and 23rd. The programme included posters, workshops and presentations (please click on ‘continue reading’ for the programme).

Thankyou to eveyone who attended, and especially the speakers. Thanks to everyone who gave their feedback.

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Early Career Researcher event

BioProNET early career researcher meeting
September 15-16th 2015, Cripps Hall, University of Nottingham

This event (two half days) featured feature career-development workshops and activities, including Myers–Briggs-type personality profiling as well as sessions from individuals in academia, industry and outside the lab highlighting various career paths (including any wrong turns!) and opportunities. There was also be the chance to attend a mock interview or a CV clinics, and speak to a recruitment agency. And the winner of The Apprentice 2012 Ricky Martin shared his experiences with us prior to dinner.

Thank you to everyone who attended and gave feedback; the programme is listed below for reference.

We are in the very early stages of planning next year’s event, which we anticipate will have a more scientific focus, for example by giving delegates the opportunity to present their research. Please get in touch with us if you have suggestions or would like to be involved in the organisation.

Scientific exchange funding awarded

Congratulations to Luis Martin, Bangor University who was awared £500 to fund a short scientific exchange with the Università degli Studi di Salerno in Italy to study the counter current fractionation of glycolipids.

“As a result of the scientific exchange, I was able to understand and master the technique of supercritical counter current fractionation,” said Luis. The visits also enabled the relationship between the two universities to be strengthened: “Two Erasmus plus stays next year have been set up, with two MEng coming over to our facilities, accounting for a total time of one year,” Luis highlights.

Read the full report here.

We have funding of up to £500 per award for early career researchers to foster short (up to 1 month) exchange visits to another lab, with the aim of developing research collaborations. The host lab can be academic or industrial but it should be working in a different discipline or should allow the applicant to learn a new technique.

The money should be used to fund the scientific exchange, such as travel to the host lab and accommodation, but should not be used for consumables or travel to conferences. BioProNET classify an early career researcher as a scientist who has spent less than 10 years in active postgraduate research. PhD students are classed as early career researchers, but individuals with a tenured position — such as a lecturership — would be excluded.

A short report will be needed at the end of the project; payment will be in arrears and receipts will be needed.

A call is currently open. Please contact Charlotte Harrison c.harrison-560@kent.ac.uk or Joanne Flannelly joanne.flannelly@manchester.ac.uk with any queries or to submit your application.