Challenges and Opportunities for Optimising Protein Glycosylation
Tuesday February 9th 2016, Imperial College London
Increasing efforts are underway to produce recombinant proteins that have a homogeneous glycan profile, which will lead to products with improved in vivo characteristics (such as half‐life and efficacy) and hence offer substantial cost benefits. Studies involve the genetic engineering of cell lines, process modifications (for example, the addition of relevant precursors) and in vitro modification of recombinant proteins. These efforts will also facilitate the use of quality by design framework for the development of biologics.
This event, jointly supported by IBCarb and BioProNET (two BBRSC networks in Biotechnology and Bioenergy), aims to bring together researchers involved in recombinant protein production with scientists involved in product characterisation.
The workshop will feature keynote speakers as well as round table discussions to identify the grand challenges that arise from the production, regulation and technical aspects of recombinant protein glycosylation. Attendees should also have the opportunity to form working groups for funding applications.
Confirmed speakers include David James (University of Sheffield) and Mitul Patel (GlaxoSmithKline).
A number of travel bursaries are available for early-stage career researchers (PhD students and post-docs) to attend this event. For more information about travel bursaries from IBCarb please see www.ibcarb.com/funding or contact Claire Doherty. For travel bursaries from BioProNET please contact Charlotte Harrison.
For more information and to register for the event please use this link. Please register no later than Monday February 1st.