Category: News

Industrial Strategy boost for UK medicine manufacturing

New initiatives to accelerate the development and manufacture of new medicines have been awarded funding from Innovate UK under the Industrial Strategy Challenge Fund. In total, 22 projects involving 58 organisations will get £15 million.

It’s great to see many of our member companies and universities being very successful and a diverse range of projects that fall within BioProNET remit!

Examples include:
University College London – Design, transfer and qualification of a commercially-scalable process for viral vectors
Synpromics and Lonza Biologics – Development of a novel inducible expression system for the manufacture of therapeutic proteins from CHO cells.
Ipsen Biopharm, CPI and Torchlight Genetics – Novel production process for a highly potent recombinant protein using doggybone DNA (dbDNA) vector and cell free expression technology

A full list of funded projects can be found here.


2018 Science Meeting prize winners

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Conratulations to the winners of the poster and short talk prizes at our 4th annual science meeting, who received their prizes from Karen Lewis of the BBSRC (far left).

The winners were Rochelle Aw, Imperial College London – 1st prize talk (pictured 2nd left); Eva Pekle, MedImmune & Univserity of Kent – 2nd prize talk (pictured middle); Tania Selas Castiñeiras, Cobra Biologics – 3rd talk prize; Hirra Hussain, University of Manchester – 1st prize poster, Natalie Talbot, University of Kent – 2nd prize poster (pictured 2nd right) and James Budge, University of Kent – 3rd poster prize (pictured far right).

IBSCA funding awarded

BioProNET has recently awarded six indistrial biotecnology seeding catalyst awards (IBSCA). This funding aims to develop and progress ideas and technology within the scope and remit of BioProNET and the call along the technology readiness level (TRL) pathway.

Pilot production of engineered nucleases with applications in molecular biology and diagnostic devices
Jon Sayers, University of Sheffield

Optimization of influenza vaccine manufacturing through inhibition of autophagy
Jeremy Rossman, University of Kent

Improved microfluidic devices for downstream bioprocess separation of sub-micron targets
Alan Goddard, Aston University

Learning from charge interactions in nature to understand poly-anion/cation complementarity in drug encapsulation
Jim Warwicker, University of Manchester

Engineering secretory capacity in S. cerevisiae strains to improve recombinant protein production yield
Campbell Gourley, University of Kent

Enhancing secretory pathway function to allow selection of host cell clones
Lisa Swanton, University of Manchester

Establishing a prototype process for manufacturing non‐therapeutic biologics expressed in plants for the R&D market
Anil Day, University of Manchester

5th Annual Science Meeting

October 10-11th 2018
British Medical Association House, Central London
Come and join the bioprocessing community at our 5th Annual Science meeting. We anticipate that the meeting will begin at 10.15am on 10th October and finish at 3pm on 11th October.

“The 2017 meeting was one of the most interesting and educational that I have attended in a while!”

March 19th – registration opens
July 6th – registration closes for places with accommodation
July 6th – deadline for short talk abstracts
September 28th – registration closes for day delegates (sooner if capacity is reached)

Designing more efficient cell-expression systems
Molecular characterisation of process quality
Building expression systems into optimised process
The clinic and beyond
Upstream meets downstream – rapid process development

Confirmed speakers
Kerstin Otte
– University of Applied Science Biberach, Germany
Colin Robinson – University of Kent
Nathan Lewis – University of California San Diego, USA Engineering CHO cells with enhanced traits with multiplex genome editing
Gary FinkaGlaxoSmithKline Developing a next-generation cell line development platform through targeted automation, analytics and informatics
Tarit Mukhopadhyay University College London Manufacturing the future at less than a $1 a dose and meeting global health needs
Caroline Barelle Elasmogen soloMERä Biologics: Site-specific therapeutic biologics for the treatment of inflammatory disease
Phil Cater Leaf Expression Systems Plant produced biologics – process economics
Paul Dalby University College London New analytical methods for chromatography OR further downstream to formulation.
Yvonne Grenzel Max Planck Institute for Dynamics of Complex Technical Systems, Germany Intensified cell-based viral vaccine processes: from continuous to perfusion and to hybrid systems.
Chris van der Walle MedImmune Manufacture and characterisation of nanoparticles encapsulating nucleic acids
Pernille Harris – Technical University of Denmark Solution structure and self-association of pharmaceutical proteins
Jonathan BonesThe National Institute for Bioprocessing Research and Training, Ireland Characterisation of biopharmaceuticals using intact protein separations hyphenated to high resolution native mass spectrometry
Laura Palomares – National Autonomous University of Mexico
Mike Betenbaugh – Johns Hopkins University, USA

Proof of Concept funding awardees
Dave Brockwell University of Leeds Investigating the effects of hydrodynamic force on the structure and biological integrity of a viral vector gene therapy product
Michael Plevin University of York Can an archaeal helicase enhance the performance of a nanopore DNA sequencer?
Gary Montague Teesside University Improved preservation of biologics by continuous intensified lyophilisation

We will also invite early career researchers to give short talks – more details to be given when registration opens

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SuperBIO & BioBase4SME – innovation support voucher

NNFCC would like to highlight an interesting funding opportunity for SMEs.
We are involved in two innovation support schemes to help SMEs commercialise their innovation: SuperBIO (H2020 funded) and BioBase4SME (Interreg funded).

Both schemes offer the opportunity to contract services from professional providers at cost prices, a significant reduction on commercial rates, additionally both schemes provide co-financing of the services. The services offered include market research, techno-economic assessment, feedstock analysis, business plan development, LCA, regulatory appraisal and process scale-up testing (both on chemical processes and IB processes, including high throughput strain engineering and process optimisation).
Through those two programs, SMEs in Europe can access services up to a value of:
€100,000 (with a SME cofunding share in cash of max. 50% from the SME) via BioBase4SME
€60,000 (with a SME cofunding share in cash of max. 25% from the SME) via SuperBIO

Conact Lucie Pfaltzgraff at NNFCC The Bioeconomy Consultants for more information.