Author: BioProNET Network

Principle scientist – cell line development

Fujifilm Diosynth Biotechnologies

 

Brief description: The successful candidate will be laboratory-based and, working as part of a team, will be involved in cell line development from transfection, cloning and selection of cell lines to evaluation of clonal cell lines in scale-down mimics of the production process)

https://www.fujifilmdiosynth.com/about-us/careers/posting/principal-scientist-3/

Applicants need to fill in the job application form which can be found on the careers site. The closing date is the 27th July

 

PhD: Novel bioprocessing strategies for the production of functional magnetic nanoparticles

Aston University –  Birmingham, UK School of Engineering and Applied Science

Applications are invited for a three-year Postgraduate studentship, supported by the School of Engineering and Applied Science, to be undertaken within the Aston Institute of Materials Research (AIMR) and the European Bioenergy Research Institute (EBRI) groups. The successful applicant will join an established experimental group working on the production of functional and biologically synthesised materials for healthcare and biotechnological applications.

GSK – Biopharmaceutical cell line development senior scientist

Role and responsibilities
The successful applicant will responsible for:
• Supporting CLD project campaigns in the laboratory and communicating updates to key stakeholders as required.
• Playing an active role in maintaining a high-performance lab environment, by managing their own time effectively, contributing to the daily upkeep of business-critical equipment and by supporting other team members to achieve shared objectives.
• Supporting next-generation CLD work packages: From conceptual ideas through to experimental delivery and data analysis. Openly sharing findings and pro-actively seeking scientific input and critique.
• Assisting in the authoring of detailed technical reports and process transfer documents required for cell bank transfer to GSK’s GMP facility and as primary information for regulatory facing documents.
• Staying current with the latest regulatory requirements and advances in cell line associated technologies. Implement findings according to business needs.
• Pro-actively working with key stakeholders (e.g. disruptive technologies, upstream process research, GMP-operations) to ensure alignment of processes and practices.
• Contributing to project and matrix teams as appropriate.
• Seeking all opportunities to develop and maintain a strong intellectual property position.
• Maintaining relationships with external professional, trade, and scientific organisations consistent with GSK business needs.

Closing date for applications: 10th July 2018

More details https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=380852&localeCode=en-us

PDRA position: downsized cell-derived peptides as potent inhibitors of alpha-synuclein toxicity

Dr Jody Mason’s lab at the University of Bath is looking for a bright and enthusiastic individual who is interested in using a new and cutting edge peptide library screening approach to derive functional peptide-based antagonists of alpha-Synuclein (aS) associated toxicity. The project is wide-ranging and will involve extensive molecular biology, peptide synthesis, and protein biochemistry to derive functional antagonists and to characterise their mechanism of action (see Cheruvara et al., J Biol Chem 2015). The project is highly collaborative and will be undertaken in collaboration with partners at Bath and the University of Queensland to provide a detailed picture of how antagonists function, including their ability to block aS associated toxicity both in vitro and within live neuronal cells, The project will require travel in the UK and possibly beyond.

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