Challenges and Opportunities for Optimising Protein Glycosylation
Tuesday February 9^th 2016, Imperial College London

Increasing efforts are underway to produce recombinant proteins that have a homogeneous glycan profile, which will lead to products with improved in vivo characteristics (such as half‐life and efficacy) and hence offer substantial cost benefits. Studies involve the genetic engineering of cell lines, process modifications (for example, the addition of relevant precursors) and in vitro modification of recombinant proteins. These efforts will also facilitate the use of quality by design framework for the development of biologics.

This event, jointly supported by IBCarb and BioProNET (two BBRSC networks in Biotechnology and Bioenergy), aims to bring together researchers involved in recombinant protein production with scientists involved in product characterisation.

The workshop will feature keynote speakers as well as round table discussions to identify the grand challenges that arise from the production, regulation and technical aspects of recombinant protein glycosylation.  Attendees should also have the opportunity to form working groups for funding applications.

Confirmed speakers include David James (University of Sheffield) and Mitul Patel (GlaxoSmithKline).

Travel bursaries:
A number of travel bursaries are available for early-stage career researchers (PhD students and post-docs) to attend this event. For more information about travel bursaries from IBCarb please see www.ibcarb.com/funding or contact Claire Doherty. For travel bursaries from BioProNET please contact Charlotte Harrison.

For more information and to register for the event please use this link. Please register no later than Monday February 1^st.

October 22nd–23rd 2015, Manchester Midland Hotel

Our second annual scientific meeting was held at the Midland Hotel, Manchester on October 22nd and 23rd. The programme included posters, workshops and presentations (please click on ‘continue reading’ for the programme).

Thankyou to eveyone who attended, and especially the speakers. Thanks to everyone who gave their feedback.

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Symposium on Metals in Bioprocessing and Membrane Transport
BioProNET, Metals in Biology and Crossing Biological Membranes networks held a symposium on metals in bioporcessing and membrane transport on March 12th at Slaley Hall, Hexham, Newcastle 2pm–4pm (running on from the Bioprocessing Research Industry Club (BRIC) meeting). Chair – Alan Dickson, University of Manchester.
2.00 – 2.15 Nigel Robinson, Durham University – Overview of metals in bioprocessing
2.15 – 2.30 Julian Rutherford, Newcastle University – Yeast systems
2.30 – 2.45 Peter Chivers, Durham University – Bacterial systems
2.45 – 3.00 Mark Smales, University of Kent – Mammalian systems
3.00 – 3.15 Coffee break
3.15 – 4.00 Industry Perspectives – led by industrialists; an open discussion and Q&A session

BioProNET held a symposium at this conference, entitled ‘Implications of synthetic biology for bioprocessing’ that featured the following presentations:

‘Overview of application of synthetic biology: Cells and Products‘ (Alan Dickson and Mark Smales from BioProNET); ‘Generation of new format biopharmaceuticals: Antibody-drug conjugates‘ (Dave Simpson, Glythera); ‘In vivo/vitro screens for inhibitors of protein aggregation: in disease and biopharmaceuticals?‘ (David Brockwell, University of Leeds); ‘Evaluation of novel format biopharmaceuticals during manufacture‘ (Paul Dalby, University College London).

BioProNET hosted an exciting international scientific meeting at in Cardiff on the 23rd and 24th October 2014, which covered the entire spectrum of bioprocessing.

Click below to see details of talks and workshops:

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