5th Annual Science Meeting

October 10-11th 2018
British Medical Association House, Central London
Come and join the bioprocessing community at our 5th Annual Science meeting.
A wait list is now in place
https://www.surveymonkey.co.uk/r/BioProNET2018wait

“The 2017 meeting was one of the most interesting and educational that I have attended in a while!”

Wednesday October 10th
9.30 Registration (if you arrive before registration you are welcome to use the BMA cafe)
10.15-10.30 Welcome, achievements and what next for BioProNET
Designing more efficient cell-expression systems chaired by Mark Smales
10.30-10.55 Kerstin Otte
 University of Applied Science Biberach, Germany Identification and characterisation of intracellular production bottlenecks in CHO cells producing complex biopharmaceuticals
10.55-11.20 Colin Robinson University of Kent Development of next generation E. coli platforms for the regulated production and periplasmic targeting of biotherapeutics 
11.20-11.30 Andrew Peden University of Sheffield Developing a toolkit for determining the manufacturability of new therapeutics in CHO cells 
11.30-11.55 Nathan Lewis University of California San Diego, USA Engineering CHO cells with enhanced traits with multiplex genome editing
11.55-12.10 Simon Saxby Leaf Expression Systems Plant produced biologics – process economics

12.10-13.15 Lunch

Building expression systems into optimised process chair TBC
13.15-13.40 Gary Finka GlaxoSmithKline Developing a next-generation cell line development platform through targeted automation, analytics and informatics
13.40-14.05 Sophia Hober Royal Institute of Technology, Sweden The human secretome project
14.05-14.15 Gary Montague Teesside University Improved preservation of biologics by continuous intensified lyophilisation
14.15-14.25 James Winterburn University of Manchester From bench to business with UKRI funding
14.25–14.50 Natalio Krasnogor Newcastle University Synthetic portabolomics: bridging the gap between the lab bench and industry to speed up the development of new biotech products

14.50-15.30 refreshment break and networking

The clinic and beyond chaired by Laura Palomares
15.30-15.55 Caroline Barelle Elasmogen soloMERä Biologics: Site-specific therapeutic biologics for the treatment of inflammatory disease
15.55-16.20 Tarit Mukhopadhyay University College London Manufacturing the future at less than a $1 a dose and meeting global health needs
16.20-16.30 Michael Plevin University of York Can an archaeal helicase enhance the performance of a nanopore DNA sequencer?
16.30-16.40 Pavlos Kotidis Imperial College London A mathematical model to describe CHO cell growth and monoclonal antibody glycosylation

Hotel check-in
18.00 Poster session
20.00 Conference dinner

Thursday October 11th
Upstream meets downstream – rapid process development chair TBC
9.00-9.25 Paul Dalby University College London New analytical methods for chromatography; further downstream to formulation
9.25-9.50 Yvonne Genzel Max Planck Institute for Dynamics of Complex Technical Systems, Germany Intensified cell-based viral vaccine processes: from continuous to perfusion and to hybrid systems
9.50-10.15 Martyn Hulley MedImmune Nucleic acid purification for biotherapeutics
10.15-10.25 Dave Brockwell University of Leeds Investigating the effects of hydrodynamic force on the structure and biological integrity of a viral vector gene therapy product
10.25-10.35 Davide Vito University of Kent Translation engineering through the non-coding genome in CHO cells
10.35-11.00 Pernille Harris Technical University of Denmark Solution structure and self-association of pharmaceutical proteins

11.00-11.40 refreshment break and networking

Molecular characterisation of process quality chaired by Alan Dickson
11.40-12.05 Mike Betenbaugh Johns Hopkins University, USA Glycoengineering of mammalian cell lines to improve product quality
12.05-12.30 Laura Palomares National Autonomous University of Mexico Challenges of bringing recombinant vaccines to the market: A case study for a influenza vaccine
12.30-12.40 Perdita Barran University of Manchester Top-down mass spectrometry methods for full characterisation of biopharmaceuticals
12.40-12.50 Rosa Morra University of Manchester Classical and non-classical secretion pathways in E. coli for periplasmic and extracellular recombinant protein production
12.50-13.15 Jonathan Bones The National Institute for Bioprocessing Research and Training, Ireland Characterisation of biopharmaceuticals using intact protein separations hyphenated to high resolution native mass spectrometry

13.15-14.00 Poster prizes and lunch
14.00-16.00 Optional collaboration-building session

Timings may change due to logistical needs

waiting list: https://www.surveymonkey.co.uk/r/BioProNET2018wait

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