Category: Jobs

Two jobs at GSK

Biopharm Analytical Scientist (immunoassay)
Stevenage, Hertfordshire

Basic qualifications: more details here

PhD or equivalent experience in an analytical, physchem or biophysics field working with biopharmaceuticals or other biotherapeutics.

Experience in developing analytical methods is essential, especially immunoassay and residual impurity assays e.g. surface plasmon resonance (SPR), biolayer interferometry (BLI), binding ELISAs, Western Blotting, 2D-DIGE analysis & qPCR.

Good understanding of ICH guidelines for analytical method development, analytical method qualification and validation and good knowledge of CMC-relevant liabilities of biopharmaceutical molecules.

Knowledge and understanding of critical quality attributes (CQA) and developing automated solutions are desirable.

Biopharm Analytical Scientist (separation)
Stevenage, Hertfordshire

Basic qualifications: more details here

PhD or equivalent experience in an analytical, physchem or biophysics field working with biopharmaceuticals or other biotherapeutics.

Experience in developing analytical methods is essential, especially chromatographic & electrophoretic assays e.g. Size exclusion chromatography (SE-HPLC), reverse phase chomratography (RP-HPLC), ion exchange chromatography (IEX-HPLC), capillary isoelectric focusing (c-IEF) and capillary gel electrophoresis (CGE).

Good understanding of ICH guidelines for analytical method development, analytical method qualification and validation and good knowledge of CMC-relevant liabilities of biopharmaceutical molecules.

Knowledge and understanding of critical quality attributes (CQA), formulation development, and developing automated solutions are desirable.

The closing date for both roles is January 19th.

Two positions at Arecor

Senior Scientist: An exciting opportunity has arisen for a talented Senior Scientist to join Arecor’s Development team. This role will appeal to an individual who is passionate about science and its application to the development of therapeutic products, whilst also offering the right individual the opportunity to take on a role where you will make a real impact on the success of a dynamic start-up company.

To be considered for this position you will have:
• An MSc or PhD in Life Sciences or equivalent (BSc considered based on experience)
• Extensive experience in an analytical laboratory environment, with hands on experience of working with a broad range of analytical methods, including HPLC, DLS, spectrophotometry, activity assays
• Possess excellent communication skills, both written and verbal including drafting protocols, summaries and reports to a very high standard
• A proven track record in problem solving including the ability to design experiments, analyse data/results and trouble-shoot issues
• Be dynamic, flexible, self-motivated and able to work both individually and within a team
• Must be prepared to travel (up to 20% of time), including overseas, if required

More details here

Scientist: As part of the Development team, we are seeking a highly self-motivated individual to play a diverse role in an innovative and expanding company. We are seeking a competent person with a minimum of 2 years of experience working on the analysis of proteins and/or bio-therapeutics to support Arecors Client and R&D portfolio. Hands on experience of HPLC is essential. The successful applicant will be a self-starter who is able to work well within a team and individually and have excellent communication and organisation skills.

To be considered for this position you will ideally have:
• A BSc or MSc in Life Sciences or equivalent, PhD advantageous
• At least 2 years’ experience in an analytical laboratory environment, with hands on experience of working with a broad range of analytical methods, including HPLC, DLS and spectrophotometry
• Possess excellent communication skills, both written and verbal
• Be an excellent problem solver with the ability to design experiments, analyse data/results and trouble-shoot
• Be dynamic, flexible, self-motivated and able to work both individually and within a team

More details here

Faculty position – University of Delaware

The Department of Chemical & Biomolecular Engineering at the
University of Delaware invites applications for a tenure-track open rank
Professor position.

REQUIREMENTS: Ph.D. or equivalent in chemical engineering or a related field.

DUTIES: The Department of Chemical & Biomolecular Engineering seeks faculty
candidates to develop and lead a vigorous and nationally recognized research
program; teach and advise students at both the undergraduate and graduate levels;
and participate in and contribute to the departmental and larger professional
community. While applications in all research areas will be considered, we particularly
seek applicants with expertise in biopharmaceutical manufacturing, bioinformatics,
and systems design and optimization, especially those that synergize with the new
manufacturing excellence centers, NIIMBL and RAPID.

APPLICATION: Please submit a curriculum vitae, a description of research and
teaching interests, and the names, addresses, telephone numbers and email addresses
of at least 3 references at apply.interfolio.com/44338. Applications will be considered
until the position is filled. The curriculum vitae and letters of recommendation will be
shared with department faculty.

Jobs at AstraZeneca / MedImmune

AstraZeneca and MedImmune have several roles available:

New – added to BioProNET site on October 16th:

https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Liverpool/Analytical-Development-associate–AS-II—-Virology_R-014811-1

https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Liverpool/Analytical-Development-scientist–Sci-I-_R-014809

https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Liverpool/QC-Technical-Support-Manager_R-015661

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Analytical Development (AS I/II) (Liverpool)
https://astrazeneca.wd3.myworkdayjobs.com/broadbean_external/job/UK—Liverpool/Analytical-Development-scientist–AS-I-II-_R-013819-2

Engineering Business Process Specialist (Liverpool)
https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Liverpool/Engineering-Business-Process-Specialist_R-012073

Cell Culture and Bioreactor Process Development: Associate Scientist II (Cambridge)
https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Cambridge/Cell-Culture-and-Bioreactor-Process-Development–Associate-Scientist-II_R-012735-1

Cell Culture and Bioreactor Process Development Scientist (Sci I) (Cambridge)
https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Cambridge/Cell-Culture-and-Bioreactor-Process-Development-Scientist–Sci-I-_R-008712

Bioreactor Scientist (AS II / SCI I) (Cambridge)
https://astrazeneca.wd3.myworkdayjobs.com/MedImmune-Careers/job/UK—Cambridge/Bioreactor-Scientist–AS-II—SCI-I-_R-008101

 

Several vacancies at F-star

F-star develops therapeutic bi-specific antibodies using its Modular Antibody Technology, directed at improving the treatment of serious diseases, with a focus on immune-oncology. We are entering an exciting period of the Company’s development and have several vacancies at the Babraham Research Campus in Cambridge, UK.

Research associate – protein sciences
You will be responsible for protein purification and subsequent routine characterisation, filtrations and sterility testing of antigens, antibody fragments and bi-specific mAb2 molecules.
• A relevant degree and/or a combination of education and experience
• Good track record of relevant hands-on, lab-based experience
• Protein purification using AKTA system (antibody purification, ion exchange, affinity chromatography; eg IMAC)
• Protein characterisation (HPLC, SDS-PAGE, endotoxin level testing etc.)
• Relevant industry experience

Research associate – molecular biology
You will be responsible for the design and execution of expression vector cloning to express antibodies and fusion proteins in mammalian systems
• Relevant experience ideally gained in an industrial environment
• Hands-on experience in molecular biology techniques and vector design for expression of antibodies in mammalian systems (DNA manipulation, cloning, sequence alignment and analysis)
• Knowledge in antibody engineering (eg isotype/subtype reformatting)

Research associate – mammalian cell culture
You will be responsible for transient and stable expression of recombinant proteins in mammalian cell lines at several lab scales.
• Relevant industry or academic experience in mammalian cell culture
• Hands-on experience in transient expression of recombinant proteins using mammalian cell systems (HEK293 and CHO)
• Knowledge in CHO cell line development including transfection, marker selection and generation of stable pools will be an advantage

Scientist – protein characterisation
you will proactively contribute to the development and delivery of analytical capabilities to support our technology platform and mAb2 bispecific pipeline.  Analytical capabilities are required to deliver protein engineering, research grade production and process development activities with a key focus on protein characterisation, developability assessments and formulation
– PhD or equivalent relevant experience, ideally gained in an industrial environment although consideration will be given to industrially relevant academic experience
– Experience and breadth of knowledge in analytical and biophysical characterisation of recombinant biotherapeutics for CMC development. (e.g. formulation, protein aggregation, protein stability and post-translational modifications including glycosylation)
– Experience in early stage developability assessment of therapeutic proteins and development lifecycle for recombinant protein therapeutics
– Demonstrated experience in establishing and applying the following techniques: dynamic and static light scattering, capillary electrophoresis, SVP, UHPLC (SEC, RP, IEX), mass spectrometry

Further details of these and other exciting roles along with instructions how to apply can be found at http://www.f-star.com/careers