Category: Jobs

Principal Scientist – Mammalian Cell Culture; Fujifilm Diosynth Biotechnologies

Fujifilm Diosynth Biotechnologies is a world leading cGMP contract development and manufacturing organisation. We currently have over 530 employees at our Billingham site and are looking to expand within R&D.  We have an exciting opportunity for a highly motivated scientist to join our R&D Mammalian Cell Culture team working to develop recombinant cell lines suitable for the manufacture of biotherapeutics.

The successful candidate will be laboratory-based and, working as part of a team, will be involved in cell line development (CLD; from transfection, cloning and selection of cell lines to evaluation of clonal cell lines in scale-down mimics of the production process). They will also have a role to play in contributing to the implementation of new and innovative ways of working.

Technical Skills
In depth Knowledge of CLD for mammalian cell lines (ideally CHO)
Good aseptic technique and knowledge of general cell culture methods
Experience of transfection and cloning techniques
Experience with high throughput cell line screening technologies, such as the ClonePix and ambr systems.

Education and experience
A life science degree (Ideally a MSc or PhD)
Relevant biotech/pharmaceutical industry experience within a mammalian cell culture role
Experience in developing stable cell lines for the production of therapeutic proteins using CHO cells

For further information please contact Fay Saunders
Closing date: 23rd June 2017

Research and Development Scientist (KTP Associate)

Closing Date : 05/06/2017
Employment Type : Fixed Term
Duration : available immediately for 24 months
Salary : £26,052 to £30,175 per annum
Location : Hart Innovations Ltd, Hartlepool
Job Reference : S&E-10099

This is an exciting opportunity for an ambitious graduate with the ability and confidence to manage a Knowledge Transfer Partnership (KTP) project with Hart Innovations Ltd.

The University of Manchester and Hart Innovations Ltd are looking to recruit a graduate in biomedical science to undertake this 24-month project which has an overall aim of producing optimised recombinant enzymes for therapeutic blood clotting diagnostic kits.

The position will  provide you with a unique opportunity to work in both an academic and biotechnology environment and play a key role in enzyme production from concept optimisation to final product and develop management skills to turn the enzyme into a commercial product,

You must be in line to, or have received a first-class degree (or equivalent) ideally in biomedical science with at least several months’ practical experience in molecular biology, recombinant protein expression and purification.

This post is funded through a Knowledge Transfer Partnership (KTP) award, a UK Government scheme intended to promote sustained and mutually beneficial relationships between universities and industry.  Based at Hart Innovations Ltd, Hartlepool you will work directly with supervisors from both the University and Hart Innovations Ltd and will use the facilities and resources of both organisations.

Please note that if you do not have permission to work in the UK, the University of Manchester will not be able to obtain a Certificate of Sponsorship for you to take up this position. All non EU/EEA candidates must have valid immigration status and/or a UK visa valid for the duration of the contract in order to be considered for this appointment.

Enquiries about the vacancy, shortlisting and interviews:
General enquiries:
Tel: 0161 275 4499

Technical support:
Tel: 01565 818 234

BBSRC CASE PhD 4 year studentship

A BBSRC CASE PhD 4 Year studentship (in partnership with GSK) isavailable from October 1st 2017. The project title is ‘Manufacturing lentiviral vectors for gene therapies: Optimisation of cellular factories’, and it is a collaboration between the University of Manchester (Dickson lab) and GSK (Stevenage), closing date for applications 20th June 2017
For more details contact

Croda: Development Scientist – Biotransformation

We currently have an opportunity for a development scientist, based in our biotransformation team at our Ditton site in Widnes. In this role, you will apply your technical knowledge to develop new and existing microbial fermentation products on the biotransformation plant, as well as providing technical support to other departments on the site. You will design and carry out laboratory experiments to support process development, optimisation, troubleshooting and scale up/scale down testing. This will involve running multiple projects of varying complexity.

As our ideal candidate, you will have excellent laboratory skills and a talent for developing innovative and creative solutions to problems. You must also have strong written and verbal communication skills, a keen eye for detail and be an enthusiastic team player. The ability to plan, organise and to prioritise your own workload as well as manage projects is essential. You will be educated to degree level in a life science related discipline with experience in microbial fermentation. Working within process development with knowledge of both upstream and downstream processing would be advantageous.

Clsing date: May 28th