Category: Events

BioProNET 4th annual science meeting

BioProNET’s flagship annual science meeting will be held at the Slate Conference Centre, Warwick on October 10th-11th 2017. Registration has now closed; please contact Charlotte to be placed on the wait list.  

Day 1 – 10th October
09:30      Registration

Designing more efficient cell-expression systems (chaired by Kelvin Lee)
10:15  Helene Faustrup Kildegaard – Technical University of Denmark: Improving CHO cell factories with CRISPR-mediated genome engineering
10:45  Short talk: Eva Pekle – University of Kent: Single cell characterisation of CHO cells
10:55  Imre Berger – University of Bristol: Baculovirus expression: old dog, new tricks
11:20  David Humphreys UCB: Protein expression demands and demanding protein expressions: protein sciences the biopharma way
11.45  Short talk: Stefanie Frank – University College London: Engineering spatial segregation within bacterial hosts for bio-therapeutic protein production
11:55  Karen CoopmanLoughborough University: Taking a holistic approach to mesenchymal stem cell culture process design
12:20  Short talk: Robyn Emmins – GlaxoSmithKline: Embedding the Berkeley Lights Beacon: a bright future for cell line development
12:30  Lunch

Building expression systems into optimised process (chaired by Helene Faustrup Kildegaard)
13:30  Paula AlvesiBET, Portugal: Insect cell platforms for production of VLPs and difficult to express proteins
14:00  Short talk: Eleanor Hanson, University of Sheffield: Changes in CHO cell epigenetics throughout cell culture
14:10  Ray OwensUniversity of Oxford: High throughput cloning and expression of recombinant proteins for structural biology
14:35  Kathryn Lilley – University of Cambridge: Quantitative mass spectrometry to determine the three dimensional relationship of the proteome
15:00  Short talk: Tania Selas Castiñeiras – Cobra Biologics: Periplasmic recombinant protein production: which signal peptide to use?
15.10  Refreshment break, networking, posters

The clinic and beyond (chaired by Paula Alves)
15:45  Leda Castilho – Federal University of Rio de Janeiro, Brazil: Production of flavivirus VLPs: zika, yellow fever and beyond
16:15  Jim Faulkner – Autolus: Process development for autologous cell products

16:45  Proof of concept funding awardees (chaired by Mark Smales)
Martin Michaelis – University of Kent: Expanding production time of mammalian cell cultures for biotechnological applications
Cleo Kontoravdi – Imperial College London: Bioreactor design space identification with product quality constraints
Gyorgy Szekely – University of Manchester: Molecular imprinting for sustainable downstream processing of biopharmaceuticals

17:15  Group check-in
18:00  Poster session and drinks reception
19:30  Conference dinner

Day 2 –11th October

Molecular characterization of process quality (chaired by Gary Lye)
09:00  Chris Roberts – University of Delaware, USA: Mechanistic approaches to stabilization of pharmaceutical proteins
09:30  Short talk: Paula Meleady – Dublin City University: Quantitative phosphoproteomic analysis of CHO cells in response to reduced culture temperature
09:40  Perdita Barran – University of Manchester: Hybrid mass spectrometry approaches to analyse biologics and distinguish biosimilars  
10:05 Chris Sellick – MedImmune: Application of custom analytics to support bioprocess development for novel biopharmaceuticals
10:30  Short talk: Stephen Perkins – University College London: CCP-SAS – its utility for the atomistic modelling of pharmaceutically-important antibody solution structures
10:40  Refreshment break, networking, posters

Upstream meets downstream: rapid process development (chaired by Chris Roberts)
11:20  Kelvin Lee – University of Delaware, USA: A host cell protein that may impact polysorbate degradation
11:50  Short talk: Mire Zloh – University of Hertfordshire: Effects of excipients on biomolecule structures during dehydration processes at low temperatures
12:00  Gary Lye – University College London: Scale-down approaches to mammalian cell culture process development and primary recovery
12:25  Short talk: Rochelle Aw – Imperial College London: Increasing ribosome content in Pichia pastoris for improved cell free protein synthesis
12.35  Simone Dimartino – University of Edinburgh: 3D printed porous media for packed bioreactors and downstream processing
13:00  Peter Levison Pall: Technology advances in continuous bioprocessing from process development into clinical manufacture
13:25  Poster prizes, lunch, meeting close


Chemistry and Industrial Biotechnology Showcase 2017

Wednesday 20th and Thursday 21st September 2017, York

This two-day conference and exhibition hosted by the Knowledge Transfer Network (KTN) is a major event to bring together industry, researchers, investors and government agencies to showcase how the UK chemistry and industrial biotechnology sectors are helping to enable growth in key UK supply chains through innovation.

Programme themes will highlight the many applications of chemistry and industrial biotechnology, ranging from healthcare to agri-food, from low carbon fuels to synthetic biology, and much more.

It includes an opportunity to attend a BioVale sponsored Networking Breakfast on Value from Unavoidable Food Waste and to take a tour of the Biorenewables Development Centre.

Registration is now open, and Exhibitor and Sponsorship packages are available for the two days.

More information:

Molecular chaperones: structure, function and application in bioprocessing

University of Kent, December 20th

This BioProNET-sponsored meetining will feature a full day of talks on the structure, function and applications in bioprocessing of molecular chaperones. Registration for the conference is free – and includes lunch!  Bursaries of up to £100 are available to cover travel costs.

For more details of the event, including bursaries, and the opportunity to present  please conact Mick Tuite.

Recent breakthroughs and new perspectives of protein aggregation

BioProNET-funded workshop: Recent breakthroughs and new perspectives of protein aggregation: measuring, predicting and controlling protein aggregation
Manchester Museum February 13th 2017
Maryam Hussain for more details or if you are interested in attending.
Confirmed participants:
Christopher Roberts, University of Delaware
Wolfgang Friess, LMU Munich
Paul Dalby, UCL
Jennifer McManus, Maynooth University
Stephen Harding, University of Nottingham
Chris Van der Walle, Medimmune

Workshop on CHO cell platforms

CHO cell platforms: Chassis for engineering improved bioprocessing

The upstream expression workshop is a ‘summit’ presenting the understanding of the cell and molecular biology of CHO cells and how this understanding offers the potential to enhance manufacture of the industrial pipeline of biopharmaceuticals (existing and developing product formats).
The workshop will be held at the Manchester Museum, University of Manchester on December 8th 2016. The event is now full, please contact Alan Dickson to be added to the wait list.