This 4-year fully-funded EPSRC CASE PhD project is a collaboration between the Departments of Biology (Dr Michael Plevin, Dr Jared Cartwright) and Computer Science (Prof Susan Stepney) at University of York and FUJIFILM Diosynth Biotechnologies (FDBK).

The goal of the project is to evaluate whether computational modelling and optimisation can predict protocols for flow­-through purification of recombinant protein targets. Flow-­through purification approaches address a real-world need for economic and flexible production of proteins in smaller amounts for more specialised or smaller markets, and would allow low volume production facilities to be located closer to the point of use.

Please contact Michael Plevin or Susan Stepney for more information.

More details and links to the application process can be found here: https://www.findaphd.com/phds/project/fully-funded-epsrc-icase-project-with-fujifilm-computational-prediction-of-purification-strategies-for-industrial-protein-production/?p142004

The Animal Cell Technology Industrial Platform (ACTIP) have opened their call for ACTIP Fellowships for 2023.

Details of the application process and criteria plus news about previous winners can be found at https://www.actip.org/fellowship/

Closing date is February 28^th 2023 and further information HERE

PhD position: Upstream processing for cell culture-based virus production

Manufacturing of next-generation vaccines and therapeutic viruses will need sustainable and highly efficient production processes with process integration on all levels. The team “Upstream Processing” in the department of “Bioprocess Engineering” at the MPI Magdeburg has developed a platform covering a large selection of cell lines, viruses and viral vectors, bioreactors, analytics and process strategies. By comparison of process options and combination of powerful unit operations, a deeper process understanding is gained allowing to achieve high yields needed for virotherapy. The increasing use of artificial intelligence/digital twins in bioprocessing and vaccinology offers many options to exploit potentials and discover bottlenecks. To further advance this platform technology, we are seeking an outstanding candidate that will support our Upstream Processing Team.

Further information and contact details can be found HERE

 The aim of this competition is to stimulate the development and manufacturing of a range of innovative formulations.

• UK-registered organisations can apply for a share of up to £5 million.
• Competition overview – Innovative technologies for intracellular drug delivery – Innovation Funding Service (apply-for-innovation-funding.service.gov.uk)

More information on additional initiatives can be found on our webpage: https://ktn-uk.org/programme/medicines-manufacturing/